'cure' New genetic clues for rheumatoid arthritis

 

An international team of researchers has found more than 40 new areas in DNA that increase the risk of rheumatoid arthritis.

The work is the largest genetic study ever carried out, involving nearly 30,000 patients.
The investigators believe new drugs could be developed to target these areas that could one day provide a cure for the disease.
The findings are published in the Journal Nature.

Erdogan vows to fight on amid corruption row in Turley

Turkish PM Recep Tayyip Erdogan says he will not step down amid corruption allegations that have forced the resignations of three ministers.

The ministers' sons were among dozens of people detained as part of a wide-ranging corruption probe.
Turkey's army has said it does not want to get involved in political arguments, in response to rumours of a coup plot.
On Friday police fired tear gas and rubber bullets to break up protests in Istanbul's Taksim Square.
Protests were also held in the capital Ankara and the third-largest city Izmir.
Protesters had chanted "catch the thief" and called for Mr Erdogan's resignation.
Police are investigating allegations of illicit money transfers to Iran and bribery for construction projects.


Dec 28,2013

India targets US nationals,What will be next

India is checking the tax status of Americans working at schools in the country, after the arrest this month of an Indian diplomat in New York.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Devyani Khobragade was handcuffed and strip-searched while in custody.
Her detention on charges of visa fraud and underpayment of her housekeeper sparked outrage in India.
India would no longer turn a blind eye to tax violations by diplomats' spouses taking up work in the country, Reuters cited an unnamed official as saying.
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Delhi has also withdrawn some privileges enjoyed by American diplomats and their families in the country, added the official.

"Spouses and children have no more immunity. So if there is a parking offence or... something else happening in Bangalore etcetera, they would be held liable."
29 Dec 2013.

Zabaleta expects City to keep pressure on Arsenal Team

City's manager of Manchester  Manuel Pellegrini takes his seat before a match against Liverpool

Manchester City defender Pablo Zabaleta has warned his team-mates they can't afford to rest on their laurels as the Premier League title race heats up.

City kept the pressure on leaders Arsenal with a 2-1 win over title rivals Liverpool on Thursday, but there is no time to savour that crucial conquest as the hectic Christmasschedule means Manuel Pellegrini's team are back in action on Saturday.

Given City's 100 percent winning record in the league at Eastlands this season, a visit from lowly Crystal Palace will be seen as a certain home victory in many quarters.

A win would take City top of the table ahead of Arsenal's trip to Newcastle on Sunday, but Argentine right-back Zabaleta knows Pellegrini's men could be punished if they underestimate a Palace side that has improved under new boss Tony Pulis.

"We have to push even more now. We know December and January is one of the key points for the big teams to make a difference because we play many games and you need to try to keep winning," Zabaleta said.

"We are very comfortable and we feel good and have huge confidence.

"At the moment we are doing well, are one point behind the leaders and that is why Crystal Palace is also a key game."

City's bitter rivals Manchester United travel to Norwich looking to build on a winning run that extended to five matches on Thursday with a 3-2 success at Hull.

United, eight points behind Arsenal in seventh place, fought back from two goals down to beat Hull and boss David Moyes believes that kind of spirited display proves the defending champions shouldn't be written off despite their spluttering start to the season.

"I never doubted us," Moyes said. "I think that tells you what Manchester United have got and hopefully it tells you a bit about David Moyes as well.

"Hopefully my teams have always been committed to trying to win games of football.

"All we can do is keep knocking away and hopefully be in there fighting come the end of the season."

The weekend's marquee match-up comes on Sunday when Chelsea host Liverpool in a battle between two sides hoping to overhaul Arsenal and City in the title race.

Third placed Chelsea are one point ahead of Liverpool and two behind Arsenal, prompting Serbian defender Branislav Ivanovic to admit the fixture will have a significant impact on the Blues' title prospects.

"It's going to be a very important game for us, one of the deciding games this season," Ivanovic said.

"We must be ready for the big fight. Our team likes to play big games and big challenges.

"I hope we're going to be ready for Liverpool, because it's a massive, massive game for us."

Liverpool manager Brendan Rodgers is confident his players will recover from their setback at City and deliver a dynamic display in another major test of their title credentials.

"We went toe-to-toe with one of the best teams in Europe. We take great confidence from that," Rodgers said of the match against City.

"That was a big statement from us. Now we are just focusing on the next game and that is all we have done during the course of this calendar year.

"That has served us well. Let's see where it takes us."

Arsenal remain the team to catch and German defender Per Mertesacker believes Thursday's 3-1 win at West Ham, which saw the Gunners hit back from a goal down to end a run of four matches without a win, is ample evidence that they are capable of lasting the pace in the title race.

A 6-3 loss against City and a frustrating 0-0 draw against Chelsea had raised questions about Arsenal, but Mertesacker said: "During the game we always believed in our strengths.

"We want to go on another good run so at the minute we are really proud we are really proud that we came back against West Ham and it shows our character."

Arsenal travel to improving Newcastle on Sunday.

Fixtures (1500GMT unless stated)

Saturday

Aston Villa v Swansea, Cardiff v Sunderland (1730GMT), Hull v Fulham, Manchester City v Crystal Palace, Norwich v Manchester United, West Ham v West Brom (1245GMT)

Sunday

Chelsea v Liverpool (1600GMT), Everton v Southampton (1330GMT), Newcastle v Arsenal (1330GMT), Tottenham vStoke (1600GMT)

On December 28, 2013

Spurs sack Villas-Boas after Liverpool rout

Russian coach Fabio Capello speaks to the press after the Brazil 2014 FIFA World Cup group stage draw 

Andre Villas-Boas has been sacked as manager of Tottenham Hotspur 17 months later in the part, the English Premier League club advertised on Monday. 

The news arrived a day after Spurs were whipped 5-0 by Liverpool at White Hart Lane, which left the north London club five points underneath the Champions League puts in seventh in the Premier League table. 

"The club can proclaim that understanding has been arrived at with head mentor, Andre Villas-Boas, for the end of his administrations," read an explanation on the Tottenham site. 

"The choice was by shared assent and in light of a legitimate concern for all gatherings. We wish Andre well for what's to come. We might make a further proclamation at the appointed time course." 

Estates Boas, 36, had likewise seen his side pulverized 6-0 at Manchester City a month ago, in spite of Spurs having contributed around £105 million ($171 million, 124 million euros) on new players throughout the nearby season. 

That consumption was, notwithstanding, counterbalanced by the offer of Gareth Bale to Real Madrid, however Spurs have scored only 15 objectives in their 16 alliance amusements this season since the Welshman left the club. 

Estates Boas' release speaks to his second back to back disappointment at a London side as he was sacked via Chelsea in March 2012 after just nine months at the Stamford Bridge steerage. 

He joined Spurs the accompanying July however regardless of heading the club to their most elevated points count of the Premier League time last season (72), they passed up a great opportunity for a Champions League place to most outstanding adversaries Arsenal. 

Talking after the drubbing by Liverpool, Villas-Boas had pledged that he might not walk far from the club. 

"The call to settle on that choice is not mine on the grounds that clearly I won't leave and I'm not a loser," he said. 

"The main thing I can do is buckle down with the players to get them again on track. This is a top-four squad yet in our Premier League structure we are not there." 

While Spurs have failed in the alliance, they fit the bill for the last 32 in the Europa League in the wake of winning each of the six of their assembly amusements and were combined with Ukrainian side Dnipro Dnipropetrovsk in Friday's draw. 

They are likewise because of play West Ham United in the quarter-finals of the League Cup on Wednesday. 

Manors Boas turns into the fifth Premier League administrator to lose his employment this season. 

Paolo Di Canio was the first to go at Sunderland, emulated by Ian Holloway at Crystal Palace and Martin Jol at Fulham, while West Bromwich Albion went separate ways with Steve Clarke on Saturday. 

Russia administrator Fabio Capello, the previous England head mentor, was quickly established as the British bookmakers' favourite to succeed Villas-Boas, who first came to noticeable quality at Porto. 

Capello has formerly worked with Spurs executive of football Franco Baldini at Roma, Real Madrid and with England, and he was in participation for the amusement against Liverpool on Sunday. 

Swansea City chief Michael Laudrup is likewise shown up for be in conflict, however the executor of Guus Hiddink precluded the encountered Dutchman of the running as he is because of come to be mentor of the Netherlands for a moment time after one year from now's World Cup. 

"I might be amazed if (Hiddink) headed off to Spurs. I could scarcely envision that event," Cees van Nieuwenhuizen told Britain's Press Association. 

"He has recently marked an agreement with Holland and he has additionally turned down offers from different nations as of late to mentor them at the World Cup, so I wouldn't take any talk of Guus set to Tottenham genuinely." 

Manchester City administrator Manuel Pellegrini communicated astonish at Villas-Boas' takeoff. 

"Continuously when an administrator is sacked, I am astounded, particularly when it is an imperative supervisor," he told a public interview. 

"He is an exceptionally junior director, he has finished great with all the groups - Porto and here in England. He didn't have room schedule-wise in both clubs, yet I am totally certain he will proceed his career.

On December 16, 2013